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. 2021 Jul 14;19:4032–4041. doi: 10.1016/j.csbj.2021.07.010

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© 2021 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Annotation of SETMAR-HA binding sites in the human genome. (A) Association of ChIP peaks with genic (exon, intron, TSS, TTS) and intergenic regions. TSS: transcription start site. TTS: transcription termination site. Left and right panels: observed and expected (computer randomized) distributions, respectively. Number of peaks: 764. (B) Detailed annotation of ChIP peaks over 11 functional genomic categories. n: number of elements in categories. Cells contain observed / expected ratios for peak counts. Warmer colours represent higher enrichment. Statistically significant enrichment is observed at TSS (p-value = 0.03), MADE1 (p-value < 2.2 × 10^-16) and ITR regions (p-value < 2.2 × 10^-16; prop. z test; level of significance: 0.05).