Table 1.

Functional annotation of SETMAR-associated genes (n = 288). Upper table: top five hits of GO-term analysis. Lower table: list of significant MAPK genes.

#term ID	term description	observed gene count	background gene count	FDR
hsa04010	MAPK signaling pathway	14	293	0.0143
IPR000742	EGF-like domain	15	225	0.0016
GO:0005515	Protein binding	128	6607	0.0409
KW-0597	Phosphoprotein	161	8067	1.90E-05
KW-0025	Alternative splicing	203	10,225	1.13E-08

Gene name	Ensemble ID	Function
ANGPT1	ENSG00000154188	angiopoietin 1
CACNA1A	ENSG00000141837	calcium voltage-gated channel subunit alpha1 A
CACNA2D1	ENSG00000153956	calcium voltage-gated channel auxiliary subunit alpha2delta 1
EFNA5	ENSG00000184349	ephrin A5
FGF1	ENSG00000113578	fibroblast growth factor 1
NTRK2	ENSG00000148053	neurotrophic receptor tyrosine kinase 2
PAK2	ENSG00000180370	p21 (RAC1) activated kinase 2
PLA2G4C	ENSG00000105499	phospholipase A2 group IVC
PRKACB	ENSG00000142875	protein kinase cAMP-activated catalytic subunit beta
PRKCB	ENSG00000166501	protein kinase C beta
SOS1	ENSG00000115904	SOS Ras/Rac guanine nucleotide exchange factor 1
STK3	ENSG00000104375	serine/threonine kinase 3
TGFA	ENSG00000163235	transforming growth factor alpha
MAP3K20	ENSG00000091436	mitogen-activated protein kinase kinase kinase 20