Table 2.
Associations between race and ER staining level in a multivariable model adjusted for age, tumor size, grade, and stage among 1,573 women with ER+/HER2− invasive breast cancer
| Predictors in multivariable model | 1–10% vs. > 50% |
11–50% < vs. > 50% |
||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Race (AAW vs. EAW) | 2.19 (1.14–4.23) | 0.019 | 2.80 (1.37–5.71) | 0.005 |
| Age at diagnosis (years) | 0.98 (0.96–1.00) | 0.078 | 0.95 (0.93–0.98) | < 0.001 |
| Tumor size (mm) | 1.00 (0.99–1.01) | 0.96 | 1.00 (0.98–1.01) | 0.92 |
| Grade (1 vs 3) | –a | –a | 0.23 (0.09–0.59) | 0.002 |
| Grade (2 vs 3) | 0.08 (0.04–0.17) | < 0.001 | 0.13 (0.06–0.28) | < 0.001 |
| Stage (Regional vs. Local) | 0.52 (0.23–1.21) | 0.13 | 0.69 (0.31–1.51) | 0.35 |
| Stage (Distant vs. Local) | 1.49 (0.43–5.12) | 0.53 | 1.23 (0.32–4.77) | 0.77 |
| Stage (Unknown vs. Local) | 1.01 (0.47–2.16) | 0.98 | 0.41 (0.15–1.14) | 0.089 |
a
No tumors were grade 1 with 1–10% ER staining