Table 3.

2018 mean adjusted direct hospital costs (95% confidence intervals) of two stage revision for periprosthetic joint infection (PJI) compared to aseptic revision in total knee arthroplasty (TKA).

Characteristic	Two Stage Revision TKA for PJI Costs (95% CI)	Aseptic Revision TKA Costs (95% CI)
Total costs	$56,900 ($54,213 – $61,014)	$24,630 ($24,212 – $25,030)
2 hospital episodes	Resection: $25,520 Reimplantation: $31,381
Medicare part A hospital services	$50,160 ($47,739 – $53,870)	$21,533 ($21,156 – $21,914)
Medicare part B professional costs	$6,742 ($6,455 – $7,153)	$3,099 ($3,061 – $3,136)
Costs by service category
Room and board	$12,937 ($11,807 – $14,693)	$4,307 ($4,197 – $4,422)
Operating room and anesthesia	$15,350 ($14,953 – $15,844)	$7,430 ($7,369 – $7,494)
Implants	$13,511 ($12,983 – $14,041)	$8,106 ($7,835 – $8,376)
Pharmacy and medications	$4,568 ($4,204 – $5,121)	$1,297 ($1,257 – $1,347)
Laboratory and pathology	$2,077 ($1,896 – $2,344)	$612 ($590 – $639)
Radiology	$548 ($443 – $709)	$188 ($170 – $206)
Physical and occupational therapy	$1,554 ($1,451 – $1,672)	$690 ($674 – $705)
ICU [number of patients]	[N=13] $24,836 ($8,080 – $47,806)	[N=26] $4,396 ($3,118 – $6,045)
Transfusion	$433 ($384 – $492)	$199 ($171 – $234)

Notes: Costs for two-stage revision TKA are calculated by combining two hospitalization episodes (resection and reimplantation). Costs for aseptic revision TKA are calculated per hospital episode. The 1,276 aseptic revision TKA include 586 revisions for wear, loosening, 366 instability and 74 fractures.