A. Hierarchical clustering of high-grade MIBC specimens in Als (a), Lee (b) and Sanchez-Carbayo 2 (c) datasets deposited in Oncomine™. Note: data on UPK3B was not available and hence could not be included. B. The distribution of LU, LU-like, BL and BL-like subtypes among specimens in the Oncomine-dataset of 151 high-grade MIBC specimens. C. Comparison of specimen subtype scores by clinical parameters. Each symbol represents an individual specimen/patient, categorized with respect to a clinical parameter as shown in the figure. P-values generated by Mann-Whitney U tests are two-tailed. D, E. Kaplan-Meier plots for CSS (D) and (OS) stratified by MCG-1 subtypes using the specimens on which follow-up data were available.