Table 3: Efficacy analysis of MCG-1 subtypes in cohort-1 and the Oncomine-dataset.

Efficacy was calculated using cut-off limits (Youden’s index) from the ROC curves to calculate metastasis, CSS, and OS. For bootstrap modeling, data were generated using 1000 iterations.

Cohort-1
Metastasis			CSS Indicator (+ = Death due to BC )
Efficacy analysis			Efficacy analysis
AUC	% Sensitivity	% Specificity	AUC	% Sensitivity	% Specificity
0.545	80.0	30.8	0.586	83.3	35.7
Bootstrap modeling			Bootstrap modeling
Mean	63.9	57.7	Mean	69.5	54.7
Median	68.0	56.3	Median	78.9	50
95% CI	17.9 – 95.8	23.1 – 100	95% CI	18.2 – 98.3	20.0 – 100
Oncomine-dataset
CSS Indicator			OS Indicator (+ = Death)
Efficacy analysis			Efficacy analysis
AUC	% Sensitivity	% Specificity	AUC	% Sensitivity	% Specificity
0.516	52.2	56.4	0.571	55.3	58.3
Bootstrap modeling			Bootstrap modeling
Mean	67.8	46.4	Mean	60.2	57.3
Median	66.7	49.0	Median	58.7	60.7
95% CI	25.0 – 90.1	21.3 – 85.9	95% CI	13.4 – 96.0	14.9 – 99.3