Table 5.

Layered Report Example Illustrating: (1) Use of Site in the Diagnosis; (2) Use of a Histological Diagnosis That Does Not Designate “Anaplasia” But the Report Still Assigns a Grade; (3) Use of the NOS Designation (Here Because the Case Could Not Be Worked up Adequately at a Molecular Level)

Cerebrum
Integrated diagnosis	Supratentorial ependymoma, NOS
Histopathological classification	Ependymoma
CNS WHO grade	3
Molecular information	Derivatives extracted from FFPE tissue were of insufficient quality for sequencing and insufficient tissue remained for FISH studies

Abbreviations: CNS, central nervous system; FFPE, formalin-fixed paraffin-embedded; FISH, fluorescence in situ hybridization; NOS, not otherwise specified.