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. 2021 Jul 26;35(6):415–432. doi: 10.1089/ars.2020.8155

FIG. 1.

FIG. 1.

Uptake, export, and recycling of iron. Dietary iron after being absorbed by intestinal cells is stored and then exported to the blood stream. Majority of the iron is utilized in the synthesis of RBC production under the stimulation of erythropoietin (a kidney hormone). Dead and senescent RBCs are phagocytosed by macrophages, resulting in the production of iron, which is again utilized for the heme production. RBC, red blood cell. Color images are available online.