Table 1.
Patient characteristics
| Characteristics | Treatment Group |
P- value |
Total, n (%) | ||
|---|---|---|---|---|---|
| NACT, n (%) |
Primary Surgery, n (%) |
||||
| Patientsa | |||||
| Age at diagnosis (y) | 0.19b | ||||
| 66-70 | 387 (31.7) |
1326 (31.6) |
1713 | (31.6) | |
| 71-75 | 379 (31.0) |
1264 (30.1) |
1643 | (30.3) | |
| 76-80 | 270 (22.1) |
1038 (24.7) |
1308 | (24.1) | |
| 80+ | 185 (15.2) |
568 (13.5) |
753 | (13.9) | |
| mean (SD) | 74.1 ± 5.6 | 74.1 ± 5.5 | 0.90c | 74.1 ± 5.5 | |
| Year of diagnosis | <0.01b | ||||
| 2000 | 69 (5.7) |
363 (8.7) |
432 | (8.0) | |
| 2001 | 57 (4.7) |
372 (8.9) |
429 | (7.9) | |
| 2002 | 80 (6.6) |
371 (8.8) |
451 | (8.3) | |
| 2003 | 89 (7.3) |
365 (8.7) |
454 | (8.4) | |
| 2004 | 70 (5.7) |
342 (8.2) |
412 | (7.6) | |
| 2005 | 89 (7.3) |
335 (8.0) |
424 | (7.8) | |
| 2006 | 79 (6.5) |
333 (7.9) |
412 | (7.6) | |
| 2007 | 82 (6.7) |
257 (6.1) |
339 | (6.3) | |
| 2008 | 90 (7.4) |
311 (7.4) |
401 | (7.4) | |
| 2009 | 93 (7.6) |
274 (6.5) |
367 | (6.8) | |
| 2010 | 100 (8.2) |
234 (5.6) |
334 | (6.2) | |
| 2011 | 99 (8.1) |
223 (5.3) |
322 | (5.9) | |
| 2012 | 109 (8.9) |
206 (4.9) |
315 | (5.8) | |
| 2013 | 115 (9.4) |
210 (5.0) |
325 | (6.0) | |
| Comorbidity index | 0.05b | ||||
| 0 | 816 (66.8) |
2956 (70.4) |
3772 | (69.6) | |
| 1 | 278 (22.8) |
865 (20.6) |
1143 | (21.1) | |
| ≥2 | 127 (10.4) |
375 (8.9) |
502 | (9.3) | |
| Marital status at diagnosis | 0.05b | ||||
| Married | 585 (47.9) |
2096 (50.0) |
2681 | (49.5) | |
| Unknown | 25 (2.0) |
128 (3.1) |
153 | (2.8) | |
| Not Married | 611 (50.0) |
1972 (47.0) |
2583 | (47.7) | |
| Race | <0.01b | ||||
| African American, non-Hispanic | 67 (5.5) |
189 (4.5) |
256 | (4.7) | |
| Hispanic | 63 (5.2) |
184 (4.4) |
247 | (4.6) | |
| Other/Unknown | 57 (4.7) |
124 (3.0) |
181 | (3.3) | |
| White, non-Hispanic | 1034 (84.7) |
3699 (88.2) |
4733 | (87.4) | |
| Region | <0.01b | ||||
| Midwest | 108 (8.8) |
497 (11.8) |
605 | (11.2) | |
| Northeast | 271 (22.2) |
874 (20.8) |
1145 | (21.1) | |
| South | 264 (21.6) |
1048 (25.0) |
1312 | (24.2) | |
| West | 578 (47.3) |
1777 (42.3) |
2355 | (43.5) | |
| Area of residence | <0.01b | ||||
| Large metropolitan | 706 (57.8) |
2151 (51.3) |
2857 | (52.7) | |
| Metropolitan | 343 (28.1) |
1299 (31.0) |
1642 | (30.3) | |
| Urban | 73 (6.0) |
272 (6.5) |
345 | (6.4) | |
| Less urban | 74 (6.1) |
391 (9.3) |
465 | (8.6) | |
| Rural | 25 (2.0) |
83 (2.0) |
108 | (2.0) | |
| SEER registry | <0.01b | ||||
| Connecticut | 102 (8.4) |
235 (5.6) |
337 | (6.2) | |
| Detroit | 59 (4.8) |
224 (5.3) |
283 | (5.2) | |
| Hawaii | 11 (0.9) |
27 (0.6) |
38 | (0.7) | |
| Iowa | 49 (4.0) |
273 (6.5) |
322 | (5.9) | |
| New Mexico | 25 (2.0) |
98 (2.3) |
123 | (2.3) | |
| Seattle | 117 (9.6) |
247 (5.9) |
364 | (6.7) | |
| Utah | 26 (2.1) |
114 (2.7) |
140 | (2.6) | |
| Kentucky | 51 (4.2) |
279 (6.6) |
330 | (6.1) | |
| Louisiana | 58 (4.8) |
257 (6.1) |
315 | (5.8) | |
| New Jersey | 169 (13.8) |
639 (15.2) |
808 | (14.9) | |
| Georgia | 155 (12.7) |
512 (12.2) |
667 | (12.3) | |
| California | 399 (32.7) |
1291 (30.8) |
1690 | (31.2) | |
| Census tract percent below poverty (Census 2000), mean (SD) | 9.6 ± 8.4 | 10.1 ± 8.5 | 0.07c | 10.0 ± 8.5 | |
| Census tract median income (Census 2000), mean (SD) (US$) | 53469.0 ± 22695.1 | 52658.0 ± 24881.0 | 0.32c | 52835.8 ± 24418.6 | |
| Census tract percent non high school graduates (Census 2000), mean (SD) | 16.2 ± 11.6 | 16.9 ± 11.9 | 0.07c | 16.7 ± 11.9 | |
| Tumor | |||||
| Size (mm) | <0.01b | ||||
| 0 -25 | 99 (8.1) |
317 (7.6) |
416 | (7.7) | |
| 26 – 50 | 109 (8.9) |
446 (10.6) |
555 | (10.2) | |
| 51 -75 | 104 (8.5) |
476 (11.3) |
580 | (10.7) | |
| 76 + | 176 (14.4) |
1241 (29.6) |
1417 | (26.2) | |
| Unknown | 733 (60.0) |
1716 (40.9) |
2449 | (45.2) | |
| Mean (SD) | 69.6 ± 55.8 | 86.1 ± 66.9 | <0.01c | 83.4 ± 65.5 | |
| Histology groupings | <0.01b | ||||
| Clear cell | 17 (1.4) |
76 (1.8) |
93 | (1.7) | |
| Endometrioid | 18 (1.5) |
271 (6.5) |
289 | (5.3) | |
| Serous | 856 (70.1) |
3180 (75.8) |
4036 | (74.5) | |
| Mucinous/Other adenocarcinomas | 330 (27.0) |
669 (16.0) |
999 | (16.7) | |
| AJCC stage | <0.01b | ||||
| Stage III | 662 (54.2) |
2967 (70.7) |
3629 | (67.0) | |
| Stage IV | 559 (45.8) |
1229 (29.3) |
1788 | (33.0) | |
| Grade | <0.01b | ||||
| Grade I | 14 (1.1) |
93 (2.2) |
107 | (2.0) | |
| Grade II | 92 (7.5) |
565 (13.5) |
657 | (12.1) | |
| Grade III/IV | 667 (54.6) |
2875 (68.5) |
3542 | (65.4) | |
| Grade Unknown | 448 (36.7) |
663 (15.8) |
1111 | (20.5) | |
a
Values are censored to maintain patient confidentiality (n ≤ 11).
b
P values were derived using the chi-square test for comparing differences between two treatment groups.
c
P values were derived using the F test for comparing means between two treatment groups.