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. 2021 Jul 29;3(1):20210026. doi: 10.1259/bjro.20210026

Table 2.

Main causes of non-CF bronchiectasis and associated CT features

Causes Type of bronchiectasis Distribution Associated and/or distinctive features
Congenital
 Mounier-Kuhn Syndrome77 NA
(Trachea and main bronchi)
Central lung regions Bronchial diverticulosis, tracheal diverticula
 Williams-Campbell Syndrome78 Varicose, cystic Sub segmental bronchi
(fourth to sixth generations)
Collapsed bronchi and distal air-trapping on expiratory CT
 α 1-Antitrypsin deficiency79 Cylindric, cystic Mainly lower lobe Panlobular emphysema
Immunologic
 Allergic bronchopulmonary aspergillosis16 Cylindric, varicose Segmental and subsegmental bronchi of central-upper lungs regions Mucous plugging (“finger-in-glove” sign)
Infectious or inflammatory
 Bacterial, mycobacterial, viral Various Various Depend on pathogens
 Swyer-James Syndrome80 Cylindric Non-specific Hyperlucent lobe or lung and air-trapping
 Chronic aspiration80 Cylindric Basal lung regions Bronchial wall thickening, tree-in-bud consolidations
Defective mucous transport
 Primary Ciliary Dyskinesia81 Varicose, cylindric Middle and lower lobes Situs inversus
 Young’s Syndrome82 Cystic Little evidence Little evidence
 Primary immunodeficiency83 Mainly cylindric Upper and mid lung regions Non-specific
Airways obstruction
 Endobronchial malignancies75 Various Focal Various
 Broncholithiasis80 Cylindric, varicose Focal, more often middle lobe Calcified lymph nodes
 Extrinsic compression75 Various Focal Various
Idiopathic Various Basal lung regions20 Various