Table 3.
Patient-level analysis of factors associated with insurance payment or out-of-pocket payment for discarded drugsa
| Covariate | GLM: insurance payment Estimate (95% CI) |
Quantile regression: insurance payment Estimate (95% CI) |
2-part model: OOP payment Estimate (95% CI) |
Quantile regression: OOP payment Estimate (95% CI) |
|---|---|---|---|---|
| High-deductible plan | −533 (−1463 to 397) | −234 (−725 to 257) | 40 (24 to 56) | 0.18 (−2.9 to 3.2) |
| Age [Reference: <50 y] | ||||
| 50–59 y | −855 (−2017 to 307) | −8.7 (−554 to 536) | −0.8 (−17 to 16) | −0.00001 (−3.4 to 3.4) |
| ≥60 y | −682 (−2132 to 768) | −56 (−735 to 622) | 13 (−9 to 34) | 0.08 (−4.1 to 4.3) |
| Weight [Reference: >200 lb (90.7 kg)] | ||||
| <150 lb (68.0 kg) | 1843 (661 to 3024) | 567 (−77 to 1211) | 34 (14 to 55) | 0.08 (−3.9 to 4.1) |
| 150-199 lb (68.0-90.3 kg) | 1420 (161 to 2680) | 193 (−370 to 755) | 21 (3 to 39) | −0.0001 (−3.5 to 3.5) |
| Place of service [Reference: office] | ||||
| Hospital | 3586 (2366 to 4806) | 775 (289 to 1262) | −17 (−32 to −2) | −0.9 (−3.9 to 2.1) |
| Cancer type [Reference: GI] | ||||
| Breast | 2158 (1020 to 3296) | 813 (110 to 1516) | 30 (8 to 51) | 0 (−4.4 to 4.4) |
| Genitourinary | −99 (−2609 to 2412) | 568 (−658 to 1793) | −14 (−50 to 21) | 2.1 (−5.5 to 9.7) |
| Gynecologic | −3321 (−5343 to −1298) | −468 (−1463 to 527) | −43 (−79 to −7) | −0.08 (−6.3 to 6.1) |
| Lung | 506 (−1379 to 2392) | 599 (−602 to 1801) | −17 (−59 to 25) | −0.69 (−8.1 to 6.8) |
| Lymphoma | 7679 (5837 to 9520) | 2071 (1143 to 2998) | 62 (37 to 87) | 1.0 (−4.8 to 6.8) |
| Other blood cancers | 9349 (683 to 11860) | 4520 (3389 to 5651) | 72 (41 to 103) | 0.92 (−6.1 to 7.9) |
| Other cancer | 4302 (1397 to 7206) | 309 (−549 to 1168) | −3 (−35 to 30) | 0 (−5.3 to 5.3) |
| Region [Reference: Northeast] | ||||
| North Central | 294 (−1185 to 1773) | −297 (−1060 to 466) | −3 (−29 to 23) | 0 (−4.7 to 4.7) |
| South | 311 (−930 to 1552) | 20 (−729 to 769) | 8 (−17 to 33) | 0.08 (−4.6 to 4.7) |
| West | 865 (−499 to 2228 | 210 (−628 to 1048) | −10 (−38 to 18) | −0.84 (−6.0 to 4.4) |
| Time on chemotherapy, mo | 1927 (1606 to 2247) | 902 (821 to 983) | 12 (10 to 15) | 0.92 (0.4 to 1.4) |
a
CI = confidence interval; GI = gastrointestinal; GLM = generalized linear model; OOP = out of pocket.