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. 2021 Jun 15;50(15):8400–8413. doi: 10.1039/d0cs00558d

Characteristics of currently-available reference datasets for use in CD analyses, and the servers on which they are available. The final column indicates the types of proteins for which the dataset may be best suited. The individual protein spectral data comprising the SP17521 and SMP18022 datasets can be downloaded from the PCDDB35.

Reference dataset Wavelength range (nm) Number of proteins Server Types of proteins
SET125 178–260 29 DichroWeb16 soluble, globular
SET225 178–260 22 DichroWeb soluble, globular
SET325 185–240 37 DichroWeb soluble, globular
SET425 190–240 43 DichroWeb soluble, globular
SET525 178–260 17 DichroWeb soluble, globular
SET625 185–240 42 DichroWeb soluble, globular and denatured proteins
SET725 190–240 48 DichroWeb soluble, globular and denatured proteins
SP17521 175–240 71 DichroWeb soluble, globular (bioinformatics definitions)
SMP18022 180–240 129 DichroWeb membrane and soluble proteins
SP175+29 175–240 79 BeStSel29 soluble, globular especially β-sheet