Fig 2. THz irradiation halts cytokinesis.

(A) Schematic representation of mitotic progression. In the process of mitosis, actin polymerization is induced to make the contractile ring, which is required for starting the division of the mother cell into two daughter cells. Then, the contractile ring is squeezed and completes cell division. Cytokinesis is generally completed within 15 minutes. (B) Percentage of cells arrested at cytokinesis. The cell cycle was synchronized to the mitosis phase with 25 μg/ml nocodazole before each experiment. Nocodazole interferes with the polymerization of microtubules and arrests the initial step of mitosis. Cells were determined to be arrested at cytokinesis when the contractile ring was retained for more than 30 minutes after the release from nocodazole. The error bars show the standard deviation of three independent experiments. More than 184 cells were measured in each experiment.