Table 1.
Clinical characteristics of 27 ICU patients with ARDS due to COVID-19 pneumonia compared with historical patients with ARDS
| COVID-19 (n = 27) |
Viral ARDS (n = 14) |
Bacterial ARDS (n = 21) |
Culture-Negative ARDS (n = 30) | |
|---|---|---|---|---|
| Age, median (IQR), yr | 63 (58–74) | 61 (43–73) | 57 (35–65) | 56 (51–64) |
| Sex, female, n (%) | 13 (48.1) | 10 (71.4) | 11 (52.4) | 15 (50.0) |
| Race, n (%) | ||||
| White | 18 (66.7) | 13 (92.9) | 19 (90.5) | 30 (100.0) |
| Black | 9 (33.3) | 1 (7.1) | 2 (9.5) | 0 (0.0) |
| Body mass index, median (IQR), kg/m2 | 34.0 (29.8–40.2) | 29.7 (27.3–34.8) | 25.2 (20.8–29.6) | 32.3 (26.5–36.4) |
| H/o chronic disease, n (%) | ||||
| Diabetes mellitus | 13 (48.1) | 5 (35.7) | 9 (42.9) | 9 (30.0) |
| Chronic renal failure | 4 (14.8) | 1 (7.1) | 4 (19.0) | 5 (16.7) |
| COPD | 7 (25.9) | 4 (28.6) | 5 (23.8) | 6 (20.9) |
| Immune suppression | 3 (11.1) | 4 (28.6) | 5 (23.8) | 8 (26.7) |
| Skilled nursing facility before admission, n (%) | 8 (29.6) | 0 (0.0) | 3 (12.5) | 0 (0.0) |
| Modified SOFA score, median (IQR)* | 7.0 (4.0–8.0) | 5.5 (4.0–6.0) | 8.0 (5.0–10.0) | 7.0 (5.0–10.0) |
Definition of abbreviations: ARDS = acute respiratory distress syndrome; COPD = chronic obstructive pulmonary disease; COVID-19 = coronavirus disease; H/o = history of; ICU = intensive care unit; IQR = interquartile range; SOFA = Sequential Organ Failure Assessment.
*
Modified SOFA scores were calculated on the day of intubation without including the neurologic score of SOFA, given that all patients were intubated and mechanically ventilated; therefore, the maximum score is 20.