Table 2.
Comparison of PET mean area under the curve (AUC0-30min) of [18F]FBAT in control vs. LPS mice at 3 or 24 h post i.v. injection of LPS.
| AUC | Control | LPS 3 h | LPS 24 h | LPS 3 h+AMG |
|---|---|---|---|---|
| Whole brain | 1678.6 ± 239.3 | 3365.4 ± 489.24∗∗ | 2411.5 ± 291.53 | 193.6 ± 93.84### |
| Cortex | 1214.6 ± 133.7 | 2194.9 ± 250.98∗∗ | 1688.5 ± 61.56 | 195.5 ± 98.80### |
| Cerebellum | 1049.5 ± 132.7 | 1702.7 ± 125.49∗ | 1614.7 ± 217.86 | 194.6 ± 95.58### |
| Brainstem | 1307.1 ± 296.3 | 2722.5 ± 652.86∗∗ | 1867.5 ± 227.00 | 219.8 ± 104.72### |
Data are mean ± SEM; n = 6 per group; ∗P < 0.05 and ∗∗P < 0.005 compared to the controls; ###P < 0.001 compared to the LPS 3 h group.