Table 3.
Comparison of PET volume distribution (Vt, mL/cm3) of [18F]FBAT in control vs. LPS mice at 3 or 24 h post i.v. injection of LPS.
V t | Control | LPS 3 h | LPS 24 h | LPS 3 h+AMG |
---|---|---|---|---|
Whole brain | 0.346 ± 0.012 | 0.404 ± 0.003 | 0.274 ± 0.068 | 0.203 ± 0.032# |
Cortex | 0.278 ± 0.006 | 0.391 ± 0.020∗ | 0.264 ± 0.036∗ | 0.222 ± 0.024# |
Cerebellum | 0.227 ± 0.001 | 0.385 ± 0.016∗∗ | 0.288 ± 0.090 | 0.250 ± 0.055# |
Brainstem | 0.295 ± 0.026 | 0.435 ± 0.040∗ | 0.315 ± 0.065 | 0.223 ± 0.036# |
Data are mean ± SEM; n = 6 per group; ∗P < 0.05 and ∗∗P < 0.005 compared to the controls; #P < 0.05 compared to the LPS 3 h group.