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. 2020 Dec 17;60(8):3872–3878. doi: 10.1093/rheumatology/keaa774

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© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, [br]distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 1 — Percentage of progression and non-progression to inflammatory arthritis in arthralgia patients with subclinical synovitis at baseline

(A) ACPA-positive patients (cohort 1, n = 37; cohort 2, n = 64; cohort 3, n = 90). Patients with subclinical synovitis at baseline (cohort 1, n = 13; cohort 2, n = 36; cohort 3, n = 31). Of these, 6, 20 and 10 patients, respectively, developed IA after 1 year of follow-up. ACPA-negative patients (cohort 1, n = 129; cohort 2, n = 409; cohort 3, n = 72). Patients with subclinical synovitis at baseline (cohort 1, n = 47; cohort 2, n = 157; cohort 3, n = 19). Of these 16, 23 and 2 patients, respectively, developed IA after 1 year of follow-up. (B) ACPA-positive patients (cohort 2, n = 43; cohort 3, n = 90). Patients with subclinical synovitis at baseline (cohort 2, n = 26; cohort 3, n = 31). Of these, 17 and 12 patients, respectively, developed IA after 3 years of follow-up. ACPA-negative patients (cohort 2, n = 292; cohort 3, n = 72). Patients with subclinical synovitis at baseline (cohort 2, n = 121; cohort 3, n = 19). Of these, 20 and 3 patients, respectively, developed IA after 3 years of follow-up.