Table 2.
Relationship between venous thrombosis and the most recent past assessment of each aPL
| aPL | No. of venous thrombotic events | Person-years | Rate per 1000 person-years | Age-adj. RR (95% CI) | P-value | |
|---|---|---|---|---|---|---|
| LA | (−) | 32 | 5660 | 5.7 | 1.00 (ref) | |
| (+) | 8 | 284 | 28.2 | 4.89 (2.25, 10.64) | <0.0001 | |
| aCL-G | (−) | 38 | 5688 | 6.7 | 1.00 (ref) | |
| (+) | 2 | 256 | 7.8 | 1.06 (0.26, 4.43) | 0.9334 | |
| aCL-M | (−) | 38 | 5704 | 6.7 | 1.00 (ref) | |
| (+) | 2 | 239 | 8.4 | 1.31 (0.32, 5.43) | 0.7123 | |
| aCL-A | (−) | 39 | 5900 | 6.6 | 1.00 (ref) | |
| (+) | 1 | 44 | 23.0 | 4.2 (0.57, 30.97) | 0.1592 | |
| aB2GPI-G | (−) | 37 | 5745 | 6.4 | 1.00 (ref) | |
| (+) | 3 | 198 | 15.1 | 2.22 (0.68, 7.23) | 0.1845 | |
| aB2GPI-M | (−) | 35 | 5267 | 6.6 | 1.00 (ref) | |
| (+) | 5 | 677 | 7.4 | 1.13 (0.44, 2.88) | 0.803 | |
| aB2GPI-A | (−) | 28 | 5168 | 5.4 | 1.00 (ref) | |
| (+) | 12 | 776 | 15.5 | 2.8 (1.42, 5.51) | 0.0029 | |
aCL-G: aCL IgG; aCL-M: aCL IgM; aCL-A: aCL IgA; aB2GPI-G: anti-β2-glycoprotein I IgG; aB2GPI-M: anti-β2-glycoprotein I IgM; aB2GPI-A: anti-β2-glycoprotein I IgA; age-adj. RR: age-adjusted rate ratio. Bold values: LA was the most predictive of venous [4.89 (2.25, 10.64), P < 0.0001] thrombosis. Anti-β2-glycoprotein I IgA positivity was also a significant risk factor for venous [2.8 (1.42, 5.51), P = 0.0029] thrombosis.