Table 2.

Binding affinities of to the SARS-CoV-2 RdRP in comparison with ritonavir, danoprevir, lopinavir, and remdesivir

No.	Name of the Ligand	Binding Free Energy (kcal/mol)
1	25(OH)D3	−8.5
2	20S(OH)D3	−8
3	Ritonavir	−8
4	Danoprevir	−7.9
5	20S(OH)L3	−7.8
6	25(OH)L3	−7.7
7	1,25(OH)2D3	−7.7
8	20S(OH)7DHC	−7.6
9	22R(OH)L3	−7.5
10	24(OH)L3	−7.5
11	25(OH)7DHC	−7.5
12	Lopinavir	−7.3
13	Remdesivir	−7.3