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. 2021 Aug 3;100(6):1303–1315. doi: 10.1016/j.kint.2021.07.015

Figure 1.

Figure 1

Representative histopathology of kidney biopsy diagnoses enriched in coronavirus disease 2019 (COVID-19) patients. (a–c) Collapsing glomerulopathy: (a) Jones methenamine silver stain showing glomerular tuft collapse with an overlying epithelial cell proliferation; bar = 20 μm; (b) Masson trichrome stain showing microcystic tubular dilation; bar = 50 μm; (c) electron photomicrograph showing podocyte foot process effacement, original magnification ×1500; (d–f) myoglobin cast nephropathy; (d) hematoxylin and eosin stain showing tubular epithelial simplification and dilation with interstitial edema; bar = 100 μm; (e) periodic acid–Schiff stain showing beaded and granular casts; bar = 20 μm; (f) myoglobin immunohistochemical stain showing positivity within intratubular casts; bar = 100 μm; (g–i): proliferative glomerulonephritis with monoclonal Ig deposits (PGMID); (g) hematoxylin and eosin stain showing mesangial expansion and endocapillary hypercellularity within a glomerulus; bar = 20 μm; (h) granular mesangial and segmental capillary loop staining for IgG; bar = 20 μm; (i) granular mesangial and segmental capillary loop staining for kappa light chain; bar = 20 μm; (j–l) acute antibody-mediated rejection in kidney allograft; (j) periodic acid–Schiff stain showing glomerulitis; bar = 20 μm; (k) periodic acid–Schiff stain showing peritubular capillaritis; bar = 20 μm; and (l) C4d immunofluorescence positive in peritubular capillaries; bar = 100 μm. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org.