Table 4.
APOL1 TaqMan polymerase chain reaction genotyping results from African American and Hispanic patients with COVID-19 (n = 107): a comparison of biopsy diagnosis to genomic risk allele status—low risk (G0/G0, G1/G0, or G2/G0) or high risk (G1/G1, G1/G2, or G2/G2)
| Diagnosis | Total number | 0 Alleles | 1 Allele | High-risk, 2 alleles | % High risk |
|---|---|---|---|---|---|
| Collapsing | 48 | 4 | 0 | 44 | 91.7 |
| Acute tubular injury | 10 | 3 | 0 | 7 | 70.0 |
| Diabetic nephropathy | 13 | 5 | 4 | 4 | 30.8 |
| Primary podocytopathies | 7 | 1 | 0 | 6 | 85.7 |
| Membranous | 5 | 3 | 2 | 0 | 0 |
| FSGS, favor secondary | 4 | 2 | 0 | 2 | 50 |
| ANCA-associated GN | 2 | 2 | 0 | 0 | 0 |
| Arterionephrosclerosis | 3 | 1 | 1 | 1 | 33.3 |
| Myoglobin casts | 3 | 1 | 2 | 0 | 0 |
| Thrombotic microangiopathy | 1 | 1 | 0 | 0 | 0 |
| Lupus nephritis | 1 | 1 | 0 | 0 | 0 |
| Light chain cast nephropathy | 2 | 1 | 1 | 0 | 0 |
| Amyloidosis | 1 | 1 | 0 | 0 | 0 |
| Cortical infarct | 1 | 1 | 0 | 0 | 0 |
| Acute interstitial nephritis | 1 | 0 | 0 | 1 | 100 |
| Hemoglobin casts | 1 | 1 | 0 | 0 | 0 |
| Cryoglobulinemic GN | 1 | 1 | 0 | 0 | 0 |
| Sickle cell nephropathy | 1 | 0 | 1 | 0 | 0 |
| C3 glomerulonephritis | 1 | 0 | 1 | 0 | 0 |
| Light chain deposition disease | 1 | 1 | 0 | 0 | 0 |
| Total low-risk | 39.3 | ||||
| Total high-risk | 60.7 | ||||
ANCA, antineutrophil cytoplasmic antibody; COVID-19, coronavirus disease 2019; FSGS, focal segmental glomerulosclerosis; GN, glomerulonephritis.