Table 2.
99 genes related to compounds of EJP and T2DM.
| Symbol name | Gene name | Symbol name | Gene name | Symbol name | Gene name |
|---|---|---|---|---|---|
| Prostaglandin G/H synthase 2 | PTGS2 | Acetylcholinesterase | ACHE | Mitogen-activated protein kinase 14 | MAPK1 |
| Prostaglandin G/H synthase 1 | PTGS1 | Epidermal growth factor receptor | EGFR | Interstitial collagenase | MMP1 |
| Mineralocorticoid receptor | NR3C2 | RAC-α serine/threonine-protein kinase | AKT1 | Hypoxia-inducible factor 1-α | HIF1A |
| β-2 Adrenergic receptor | ADRB2 | Vascular endothelial growth factor A | VEGFA | Signal transducer and activator of transcription 1-α/β | STAT1 |
| Urokinase-type plasminogen activator | PLAU | Apoptosis regulator Bcl-2 | BCL2 | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
| Sodium channel protein type 5 subunit α | SCN5A | Bcl-2-like protein 1 | BCL2L1 | Peroxisome proliferator-activated receptor gamma | PPARG |
| 5-Hydroxytryptamine 2A receptor | HTR2A | Proto-oncogene c-Fos | FOS | Heme oxygenase 1 | HMOX1 |
| Sodium-dependent serotonin transporter | SLC6A4 | Cyclin-dependent kinase inhibitor 1 | CDKN1A | Cytochrome P450 3A4 | CYP3A4 |
| D (2) dopamine receptor | DRD2 | Apoptosis regulator BAX | BAX | Cytochrome P450 1A2 | CYP1A2 |
| Estrogen receptor | ESR1 | 72 kDa type IV collagenase | MMP2 | Caveolin-1 | CAV1 |
| Androgen receptor | AR | Interleukin-10 | IL10 | Myc proto-oncogene protein | MYC |
| Peroxisome proliferator-activated receptor-γ | KCNH2 | Proepidermal growth factor | EGF | Tissue factor | F3 |
| Estrogen receptor β | ESR2 | Retinoblastoma-associated protein | RB1 | Gap junction α-1 protein | GJA1 |
| Mitogen-activated protein kinase 14 | MAPK14 | Tumor necrosis factor | TNF | Intercellular adhesion molecule 1 | ICAM1 |
| Glycogen synthase kinase-3 β | GSK3β | Transcription factor AP-1 | JUN | C-C motif chemokine 2 | CCL2 |
| Cell division protein kinase 2 | CDK2 | Caspase-3 | CASP3 | E-selectin | SELE |
| Nitric oxide synthase, inducible | NOS2 | Cellular tumor antigen p53 | TP53 | Vascular cell adhesion protein 1 | VCAM1 |
| Collagenase 3 | MMP13 | Ornithine decarboxylase | ODC1 | Interleukin-8 | CXCL8 |
| Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit, γ isoform | PIK3CG | Xanthine dehydrogenase/oxidase | XDH | Protein kinase C β type | PRKCB |
| Dipeptidyl peptidase IV | DPP4 | Caspase-8 | CASP8 | Heat shock protein β-1 | HSPB1 |
| Stromelysin-1 | MMP3 | RAF proto-oncogene serine/threonine-protein kinase | RAF1 | Transforming growth factor β-1 | TGFB1 |
| Coagulation factor VII | F7 | Superoxide dismutase (Cu-Zn) | SOD1 | Maltase-glucoamylase, intestinal | MGAM |
| Nitric oxide synthase, endothelial | NOS3 | Protein kinase C alpha type | PRKCA | Interleukin-2 | IL2 |
| Tissue-type plasminogen activator | PLAT | Interferon gamma | IFNG | Poly (ADP-ribose) polymerase 1 | PARP1 |
| Thrombomodulin | THBD | Interleukin-1α | IL1A | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
| Plasminogen activator inhibitor 1 | SERPINE1 | Myeloperoxidase | MPO | Collagen α-1 (III) chain | COL3A1 |
| Collagen α-1 (I) chain | COL1A1 | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | Serine/threonine-protein kinase Chk2 | CHEK2 |
| C-reactive protein | CRP | C-X-C motif chemokine 10 | CXCL10 | Osteopontin | SPP1 |
| Runt-related transcription factor 2 | RUNX2 | Cathepsin D | CTSD | Insulin-like growth factor-binding protein 3 | IGFBP3 |
| Insulin-like growth factor II | IGF2 | Serum paraoxonase/arylesterase 1 | PON1 | Cytosolic phospholipase A2 | PLA2G4A |
| CD40 ligand | CD40LG | Type I iodothyronine deiodinase | DIO1 | Canalicular multispecific organic anion transporter 1 | ABCC2 |
| Receptor tyrosine-protein kinase erbB-3 | ERBB3 | Catalase | CAT | Serine/threonine-protein kinase mTOR | MTOR |
| Insulin receptor | INSR | Peroxisome proliferator-activated receptor-α | PPARA | Peroxisome proliferator-activated receptor δ | PPARD |