Figure 4.

Effect of DBT on fibrotic markers and collagen production in rats with PF. (a) Masson-trichrome staining of lung tissues (scale bar = 50 μm) and Ashcroft scores (n = 18). (b) HA and HYP levels in lung tissue (n = 8). (c) Alpha-SMA, collagen I, and collagen III proteins examined by Western blotting (n = 3). 1, sham group; 2, model group; 3, prednisone group; 4, DBT group. ∗∗P < 0.01 versus sham group; #P < 0.05 and ##P < 0.01 versus model group.