Table 1.
Proteins with a Log2foldchange (Log2FC) greater than 1 are highlighted in bold, and proteins with a Log2FC less than -1 are not in bold.
| UniProt accession number | Protein | Gene name | Protein reference described | Log2FC Median (min; max) |
n/6 |
|---|---|---|---|---|---|
| LPS T50 | |||||
| P06765 | Platelet factor 4 ∗ | Pf4 | [ 12 ] | 3.31 (1.02; 5.20) | 5/6 |
| D3ZFH5 | Inter-alpha-trypsin inhibitor heavy chain 2 | Itih2 | — | 1.25 (1.08; 2.34) | 4/6 |
| P26644 | Beta-2-glycoprotein 1 ∗ |
Apoh
B2GPI |
[ 13 ] | 1.45 (1.03; 1.55) | |
| O55004 | Ribonuclease 4 | RNase 4 | — | 1.78 (1.70; 2.90) | |
| P00697 | Lysozyme C-1 ∗ | Lyz1 | [ 14 ] | 1.77 (1.70; 2.63) | |
| P23764 | Glutathione peroxidase 3∗ | Gpx3 | [15] | -2.58 (-1.45; -4.75) | 4/6 |
|
| |||||
| LPS T90 | |||||
| P17475 | Alpha-1-antiproteinase ∗ | Serpina1 | [ 16 ] | 3.73 (2.97; 5.65) | 5/6 |
| Q99PS8 | Histidine-rich glycoprotein ∗ | Hrg | [ 17 ] | 2.39 (1.37; 3.89) | |
| D3ZFH5 | Inter-alpha-trypsin inhibitor heavy chain 2 | Itih2 | — | 1.92 (1.58; 3.82) | 4/6 |
| Q9QUH3 | Apolipoprotein A-V ∗ | Apoa5 | [ 18 ] | 1.44 (1.00; 2.24) | |
| P24594 | Insulin-like growth factor-binding protein 5 | Igfbp5 | — | 2.14 (1.02; 3.79) | |
| P08650 | Complement C5 ∗ | C5 | — | 5.27 (3.28; 6.21) | |
| O55004 | Ribonuclease 4 | Rnase4 | — | 1.68 (1.28; 2.32) | |
| D3ZTE0 | Coagulation factor XII ∗ | F12 | [ 19 ] | 1.42 (1.32; 1.73) | |
| P00697 | Lysozyme C-1 ∗ | Lyz1 | [ 14 ] | 2.86 (1.25; 3.81) | |
| Q6IRK9 | Carboxypeptidase Q | Cpq | — | 1.94 (1.05; 3.34) | |
| P04638 | Apolipoprotein A-II∗ | Apoa2 | [20] | -1.96 (-1.19; -5.20) | 5/6 |
| P55797 | Apolipoprotein C-IV | Apoc4 | — | -1.88 (-1.37; -2.91) | |
| P20767 | Ig lambda-2 chain C region | N/A | — | 2.39 (-1.50; -3.30) | |
| Q8R2H5 | Phosphatidylinositol-glycan-specific phospholipase D∗ | Gpld1 | [21] | -1.48 (-1.02; -2.72) | |
| P14630 | Apolipoprotein M∗ | Apom | [22] | -2.94 (-1.46; -4.82) | |
| P23764 | Glutathione peroxidase 3∗ | Gpx3 | [15] | -2.05 (-1.48; -3.44) | |
| Q68FP1 | Gelsolin∗ | Gsn | [23] | -2.05 (-1.67; -4.47) | 4/6 |
| P06759 | Apolipoprotein C-III | Apoc3 | — | -2.60 (-1.08; -3.66) | |
| P55159 | Serum paraoxonase/arylesterase 1∗ | Pon1 | [24] | -2.15 (-1.17; -2.49) | |
| P02651 | Apolipoprotein A-IV | Apoa4 | — | -1.54 (-1.04; -2.61) | |
| P35859 | Insulin-like growth factor-binding protein complex acid labile subunit | Igfals | — | -2.49 (-2.20; -2.90) | |
| P10960 | Prosaposin∗ | Psap | [25] | -2.57 (-1.53; -3.90) | |
N represent the number of rats in which the protein has been found to be deregulated over the 6 rats. Proteins with an asterisk have already been described by other reports in the context of sepsis and septic shock.