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. Author manuscript; available in PMC: 2022 Mar 8.
Published in final edited form as: Sex Dev. 2021 Mar 8;14(1-6):51–59. doi: 10.1159/000513878

Table 1:

Top enriched motifs in COUP-TFII binding sites

Homer known motif enrichment (Top five)
Upstream (>1kb TSS) (Total Target Sequences=1220, Total Background Sequences=48350)
Rank Motif Name log P-value % of Targets (Background) Sequences with Motif
1 graphic file with name nihms-1668793-t0003.jpg EAR2(NR)/K562-NR2F6-ChIP-Seq(Encode)/Homer −3.374e+02 52.95% (19.62%)
2 graphic file with name nihms-1668793-t0004.jpg COUP-TFII(NR)/Artia-Nr2f2-ChIP-Seq(GSE46497)/Homer −3.275e+02 60.25% (25.65%)
3 graphic file with name nihms-1668793-t0005.jpg COUP-TFII(NR)/K562-NR2F1-ChIP-Seq(Encode)/Homer −3.044e+02 53.11% (21.08%)
4 graphic file with name nihms-1668793-t0006.jpg TR4(NR),DR1/Hela-TR4-ChIP-Seq(GSE24685)/Homer −3.036e+02 16.97% (1.75%)
5 graphic file with name nihms-1668793-t0007.jpg RARa(NR)/K562-RARa-ChIP-Seq(Encode)/Homer −1.772e+02 62.13% (35.81%)
TSS (<1kb TSS) (Total Target Sequences=5140, Total Background Sequences=43503)
Rank Motif Name log P-value % of Targets (Background) Sequences with Motif
1 graphic file with name nihms-1668793-t0008.jpg COUP-TFII(NR)/Artia-Nr2f2-ChIP-Seq(GSE46497)/Homer −5.340e+02 42.28% (21.94%)
2 graphic file with name nihms-1668793-t0009.jpg EAR2(NR)/K562-NR2F6-ChIP-Seq(Encode)/Homer −4.737e+02 33.43% (16.01%)
3 graphic file with name nihms-1668793-t0010.jpg COUP-TFII(NR)/K562-NR2F1-ChIP-Seq(Encode)/Homer −4.561e+02 34.54% (17.12%)
4 graphic file with name nihms-1668793-t0011.jpg RARa(NR)/K562-RARa-ChIP-Seq(Encode)/Homer −2.502e+02 42.87% (28.34%)
5 graphic file with name nihms-1668793-t0012.jpg THRb(NR)/Liver-NR1A2-ChIP-Seq(GSE52613)/Homer −2.127e+02 60.83% (46.61%)