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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Transl Res. 2021 Mar 9;235:32–47. doi: 10.1016/j.trsl.2021.03.005

Fig 3.

Fig 3.

Effect of terazosin treatment on contrast-mediated elevation of serum creatinine, BUN and kidney injury molecule-1. (A) Serum creatinine, (B) blood urea and kidney injury molecule-1 were estimated at base line (BL), 28 days after nephrectomy; day 0 of contrast administration (D0), day 2 (D2) and day 7 (D7) after contrast or saline administration. Mice were administered an IP injection of 2 mg/kg terazosin in 50 μL saline to the CI+T group or saline to the CI group and S group every 12 hours starting 1 hour before contrast administration. S, mice with saline administration IP; CI, mice with contrast administration; CI + T, mice with contrast administration plus terazosin IP injection. ANOVA with repeated measurements was performed with post hoc Student t-test. Each bar represents mean ± SEM of 5–7 animals per group. * indicates P < 0.05. Superscripts (* or #) indicate a P < 0.05 compared to BL data (P < 0.05).