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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Ocul Surf. 2021 Mar 26;21:313–330. doi: 10.1016/j.jtos.2021.03.003

Table 2.

Membrane-Associated Mucins Expressed at the Human Ocular Surface

Symbol Total amino acids of protein backbone Predicted mass of protein backbone Number of Isoforms listed in NCBI Gene Number of amino acids in cytoplasmic tail
MUC16 14,507 1,519 kDa 14 31
MUC4 7,418 734 kDa 4 22
MUC22 1,786 175 kDa 3 92
MUC20 709 72 kDa 4 N/A*
MUC21 626 60 kDa 3 66
MUC1 484** 50 kDa 20 72

Protein data derived from the NCBI Protein database; listed here is the amino acid number of the longest isoform identified in the database

Estimated molecular weight of the protein backbone mass was computed using:https://web.expasy.org/compute_pi/

*

MUC20 is membrane-associated, but does not appear to be transmembrane

**

A longer isoform of MUC1, thus far only identified in cancer cells (1255 amino acids) is listed in the UniProtKB database