Table 2.
Symbol | Total amino acids of protein backbone | Predicted mass of protein backbone | Number of Isoforms listed in NCBI Gene | Number of amino acids in cytoplasmic tail |
---|---|---|---|---|
MUC16 | 14,507 | 1,519 kDa | 14 | 31 |
MUC4 | 7,418 | 734 kDa | 4 | 22 |
MUC22 | 1,786 | 175 kDa | 3 | 92 |
MUC20 | 709 | 72 kDa | 4 | N/A* |
MUC21 | 626 | 60 kDa | 3 | 66 |
MUC1 | 484** | 50 kDa | 20 | 72 |
Protein data derived from the NCBI Protein database; listed here is the amino acid number of the longest isoform identified in the database
Estimated molecular weight of the protein backbone mass was computed using:https://web.expasy.org/compute_pi/
MUC20 is membrane-associated, but does not appear to be transmembrane
A longer isoform of MUC1, thus far only identified in cancer cells (1255 amino acids) is listed in the UniProtKB database