Table 5.
Children's and mothers' SLC6A4 methylation levels and cardiometabolic biomarkers.
| Child's BMI percentile at baseline | p-value | Child's waist circumference at baseline | p-value | Mother's DBP at follow-up | p-value | |
|---|---|---|---|---|---|---|
| n = 69 | n = 62 | n = 32 | ||||
| B (SD) | B (SD) | B (SD) | ||||
| SLC6A4 | ||||||
| Average | −11.75 (3.63) | 0.002 | −4.63 (1.54) | 0.004 | 4.10 (1.61) | 0.016 |
| CpG 1 | −3.91 (1.73) | 0.027 | −2.00 (0.71) | 0.007 | – | – |
| CpG 2 | – | – | −2.49 (1.39) | 0.078 | 3.46 (1.49) | 0.027 |
| CpG 3 | −6.01 (3.27) | 0.070 | −2.91 (1.34) | 0.033 | 3.64 (1.62) | 0.032 |
| CpG 4 | −5.84 (2.95) | 0.052 | – | – | 3.55 (1.24) | 0.007 |
| CpG 5 | −5.94 (2.60) | 0.025 | −2.24 (1.08) | 0.042 | 3.28 (1.23) | 0.012 |
| CpG 6 | −7.00 (2.52) | 0.007 | −2.12 (1.20) | 0.082 | 2.52 (1.15) | 0.036 |
B, Beta, represents unstandardized regression coefficients; SD, standard deviation. Only significant (bolded) or marginalized (italicized) findings are presented.