TABLE 2.

Longitudinal mixed effects models of medication-taking by group

	Model 1 Pill-taking Time of Day		Model 2 Variability in pill-taking time (minutes)		Model 3 Number of days missed
Covariate	β Coefficient	P-value	β Coefficient	P-value	β Coefficient	P-value
Incident MCI vs. Stable cognitively intact	−17.46	.83	−10.1	.75	2.02	.28
Monitoring time	0.07	<.001	0.41	.42	0.001	.015
Incident MCI * monitoring time	0.46	<.001	4.0	.003	0.002	.17
Age (years)	4.05	.27	−1.5	.36	−0.11	.26
Female vs. male	−45.7	.61	35.1	.19	−0.15	.92

Note. Model 1 metric is in daily units, Model 2 and 3 metrics are aggregated into monthly units.

Longitudinal models for pill-taking time of day are measured in minutes from 5am each day.

Stable cognitively intact (n = 55) vs. Incident MCI (n = 9)