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. 2021 Jul 29;15:3289–3312. doi: 10.2147/DDDT.S307113

Table 8.

Target Prediction of Imidazole Derivatives as Anti-Microbial

Compounds Codes GPCR Ligand Ion Channel Modulator Kinase Inhibitor Nuclear Receptor Ligand Protease Inhibitor Enzyme Inhibitor Reported Target Reference
Imidazole Derivatives as Anti-microbial
M18 −0.10 −0.48 −0.21 −0.46 −0.27 −0.19 ND [30]
M19 0.34 0.22 0.03 0.06 0.08 0.29 ND [31]
M20 0.36 0.15 0.22 0.04 −0.14 0.22 ND [31]
M21 0.01 −0.53 −0.35 −0.54 −0.25 0.04 Double strand DNA helix breakage [32]
M22 −2.04 −3.48 −2.85 −3.16 −1.60 −2.52 ND [33]
M23 −0.62 −0.89 −0.62 −0.77 −0.62 −0.57 ND [34]
M24 0.05 0.07 0.04 −0.28 −0.41 0.00 ND [35]
M25 0.20 0.13 0.18 −0.19 −0.28 0.11 ND [37]
M26 0.31 0.12 0.17 0.12 −0.02 0.61 CYP51 [36]
M27 −0.89 −1.48 −0.30 −1.93 −1.54 −0.67 Kinase inhibitor [37]
M28 −0.27 0.08 −0.43 −0.51 −0.28 −0.18 ND [38]
M29 −0.12 −0.26 −0.11 0.27 −0.44 0.10 ND [39]