Table 9.

The Target Prediction of Imidazole Derivatives as Anti-Inflammatory

Compounds Codes	GPCR Ligand	Ion Channel Modulator	Kinase Inhibitor	Nuclear Receptor Ligand	Protease Inhibitor	Enzyme Inhibitor	Reported Target	Reference
Imidazole Derivatives as Anti-inflammatory
I30	0.42	0.32	0.67	−0.10	0.12	0.24	COX-2 enzyme	[45]
I31	0.17	0.08	0.48	−0.23	−0.25	0.32	COX-1,2 5-LOX, sPLA2-V Inhibition	[50]
I32	−0.12	−0.55	−0.27	−0.56	−0.61	−0.24	COX-2 enzyme	[47]
I33	0.05	−0.06	−0.19	0.02	−0.24	0.21	p65 NF-κB	[49]
I34	0.64	0.15	0.26	0.03	0.28	0.72	NF-κB	[48]
I35	0.05	0.07	0.04	−0.28	−0.41	0.00	ND	[35]
I36	0.21	0.12	0.18	−0.15	−0.29	0.16	ND	[35]
I37	−0.13	0.09	0.08	−0.69	−0.44	−0.07	ND	[44]
I38	−0.10	−0.57	−0.58	−054	−0.50	−0.23	ND	[46]
I39	−0.11	−0.19	0.07	−0.36	−0.23	−0.14	ND	[51]