Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 2;11:15655. doi: 10.1038/s41598-021-95165-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

GO term enrichment analyses of proteins associated with Segment A as the core CXXC5 promoter element using the STRING interaction database. Nuclear extracts of MCF7 cells were incubated overnight with a 5′-end biotinylated PCR amplicon containing Segment A or a fragment of Exon10 as the control followed by precipitation with streptavidin-conjugated magnetic beads. Bound proteins were then subjected to MS for protein IDs. Proteins are grouped under the headings of Gene Expression [GO: 0010467 Regulation of gene expression (red) and GO: 0010468, Gene expression (Blue)]; Transcription Factor/co-Regulator [GO: 0000981, DNA-binding transcription factor activity (red), GO:0008134, Transcription factor binding (blue), and GO: 0003712, Transcription co-regulator activity (green)]; Chromatin and Histone [GO: 0006325, Chromatin organization (red) and GO: 0016570, Histone modification (blue)]; RNA Processing [GO: 0006396, RNA processing (red)]; and DNA Modifications [GO: 0006281, DNA repair (red) and GO: 0071103, Conformational changes (blue)].