Table 5.
Bivariate and multivariate cox regression analysis of predictors of mortality (n = 26).
| Variables | Category | Outcome | HR (95% CI) | P-value | AHR (95% CI) | P-value | |
|---|---|---|---|---|---|---|---|
| Survive | Death | ||||||
| 177 | 26 | ||||||
| Hyperkalemia | No | 155 | 10 | Reference | Reference | ||
| Yes | 22 | 16 | 12.1 (5.23, 27.99) | 0.000 | 3.61(1.12, 11.71) | 0.032* | |
| Stage of AKI | Stage 1 | 65 | 4 | Reference | Reference | ||
| Stage 2 | 41 | 7 | 1.30(0.08, 20.88) | 0.851 | 1.7(0.10, 29.04) | 0.691 | |
| Stage 3 | 71 | 15 | 12.27(2.74, 49.8) | 0.003 | 9.6(1.17, 28.52) | 0.035* | |
| Sepsis | No | 153 | 18 | Reference | Reference | ||
| Yes | 24 | 8 | 8.1(3.69–17.79) | 0.000 | 3.12(0.95, 10.17) | 0.059 | |
| Anemia | No | 157 | 18 | Reference | Reference | ||
| Yes | 20 | 8 | 9.47(3.14, 28.89) | 0.000 | 0.40(0.07, 2.109) | 0.281 | |
| LOHS (days) | ≤ 7 | 9 | 17 | Reference | Reference | ||
| > 7 | 168 | 9 | 0.05(0.02, 0.13) | 0.000 | 0.19(0.05, 0.73) | 0.012* | |
| Dur–AKI(days) | 1–2 | 33 | 2 | Reference | Reference | ||
| 3–6 | 50 | 2 | 0.32(0.04, 2.3) | 0.251 | 1.09(0.12, 10.05) | 0.935 | |
| ≥ 7 | 94 | 22 | 4.28(1.05, 18.3) | 0.049 | 7.046(1.37, 36.08) | 0.019* | |
| Need for RRT | No | 167 | 16 | Reference | Reference | ||
| Yes | 14 | 6 | 12.4(5.04, 30.78) | 0.000 | 2.15(1.04, 4.76) | 0.061 | |
| Age in years | 18–30 | 24 | 4 | Reference | Reference | ||
| 30–60 | 108 | 9 | 2.35(0.29, 18.62) | 0.416 | 1.5(0.17, 12.01 | 0.725 | |
| ≥ 60 | 45 | 13 | 7.93(1.05, 59.95) | 0.045 | 3.03(0.35, 26.45) | 0.316 | |
AKI, acute kidney injury; HR, hazard ratio; AHR, adjusted hazard ratio; CI, confidence interval; LOHS, length of hospital stay; Dur-AKI, duration of AKI; RRT, renal replacement therapy.
*Statistically significant.