Table 2.

Baseline characteristics of studies included in the systematic review and meta-analysis for the relationship between serum Lp(a) levels and risk of ischemic stroke subtypes based on TOAST classification.

S. no.	Author name and year	Ethnicity	Study design	Sample size (IS)	Sample size (LAA)	Sample size (SVD)	Sample size (CE)	Sample size (UDE)	Sample size (ODE)	Sample size (control)	LPA assay method	LPA cut off value	LPA timepoint	Follow up duration	NOS quality score
1.	Shintani et al., 199333	Asian	Case–control study	45	9	34	NA	NA	NA	81	ELISA	≥ 42.6 mg/dl	Within 4 weeks		5
2.	Tang et al., 201972	Asian	Retrospective cohort study	226	119	107	NA	NA	NA	NA	Immunoturbidimetry	30 mg/dl	Within 2 h	NA	7
3.	Cerrato et al., 200273	Caucasian	Prospective cohort study	202	119	83	NA	NA	NA	NA	NA	NA	Within 3 months	NA	6
4.	Sun et al., 200345	Asian	Case–control study	1326	809	517	NA	NA	NA	1817	ELISA		Within 6 weeks		7
5.	Botet et al., 199248	Caucasian	Case–control study	76	48	28	NA	NA	NA	100	Electro immunoassay	NA	NA	NA	5
6.	Markus et al., 199751	Caucasian	Case–control study	163	49	37	62		15	91	ELISA	40 mg/dl	NA	NA	5
7.	Chakraborty et al., 201353	Asian	Case–control study	100	35	21	19	22	3	120	Immunoturbidimetric method		At 1, 7 days, 3 and 6 months	NA	6
8.	Lindgren et al., 199263	Caucasian	Case–control study	119	NA	41	33	35	10	159	Radioimmunoassay	NA	NA	NA	5
9.	Slowik et al., 200274	Caucasian	Case–control study	71	30	41	NA	NA	NA	30	Immunonephelometric assay	> 30 mg/ml	Within 8 months	NA	4
10.	Kooten et al., 199664	Caucasian	Case–control study	119	71	48	20	12		274	Two-site immunoradiometric assay	NA	NA	NA	6
11.	Petersen et al., 200766	Caucasian	Case–control study	254	71	53	62	51	17	63	Double-antibody ELISA	30 mg/dl	NA	NA	6
12.	Saito et al., 199767	Asian	Case–control study	118	13	35	21	17		95	Sandwich ELISA	NA	NA	NA	5
13.	Yokohawa et al., 200875	Asian	Cross-sectional study	161	87	55	19	NA	NA	NA	ELISA	NA	NA	NA	4