Table 3.
Baseline characteristics of studies included in the systematic review and meta-analysis for the relationship between serum Lp(a) levels and risk of intracerebral haemorrhage (ICH).
| S. no. | Author name and year | Ethnicity | Study design | Sample size (ICH/control) | ICH age, years | Control age, years | Source of control | Matching criteria | LPA assay method | LPA cut -off value | LPA assay timepoint | Follow up duration | NOS quality score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fu et al., 202038 | Asian | Case–control study | 196/392 | 57.9 ± 13.7 | 57.9 ± 13.7 | HB | Age and sex | Latex agglutination turbidimetric method | 23.2 mg/dl | NA | NA | 7 |
| 2. | Sun et al., 200345 | Asian | Case–control study | 499/1817 | 58.2 ± 9.7 | 59.6 ± 8.5 | PB | NA | ELISA | Within 6 weeks | NA | NA | 7 |
| 3. | Pena-Diaz et al., 200358 | Caucasian | Case–control study | 105/91 | 62.5 ± 10.6 | 40.2 ± 13.1 | HB | NA | Immunonephelometric method | > 22.45 mg/dl | NA | NA | 6 |
| 4. | Lindgren et al., 199263 | Caucasian | Case–control study | 12/159 | 68.9 ± 11.6 | 60 ± 11.5 | PB | Age | Radioimmunoassay | NA | NA | NA | 5 |
| 5. | Kooten et al., 199664 | Caucasian | Case–Control Study | 21/274 | 50.2 ± 7.4 | HB | NA | Two-site immunoradiometric assay | NA | NA | NA | 4 | |
| 6 | Saito et al., 199767 | Asian | Case–control study | 32/95 | 64 ± 11 | HB | NA | Sandwich ELISA | NA | NA | NA | 4 | |
| 7 | Seki et al.,199769 | Asian | Case–control study | 64/37 | 62 ± 9 | 61 ± 20 | HB | NA | ELISA | NA | NA | NA | 5 |