Table 1.
Clinical, blood laboratory, arterial gas analyses and CT results in patients with COVID-19 pneumonia.
| Training (March 7–April 21, 2020) set | Validation (August 18–November 8, 2020) set | |||||
|---|---|---|---|---|---|---|
| No ICU admission (n = 44) | ICU admission (n = 19) | p value | No ICU admission (n = 42) | ICU admission (n = 10) | p value | |
| Age, years | 68 ± 12 | 66 ± 10 | 0.27 | 61 ± 3 | 72 ± 7 | 0.006 |
| Gender | 0.55 | 1 | ||||
| Male | n = 32 (73%) | n = 12 (63%) | n = 23 (58%) | n = 7 (58%) | ||
| Female | n = 12 (27%) | n = 7 (37%) | n = 17 (42%) | n = 5 (42%) | ||
| Comorbodities | 0.58 | 0.59 | ||||
| 0 | n = 4 (11%) | n = 4 (27%) | n = 11 (30%) | n = 2 (20%) | ||
| 1 | n = 19 (51%) | n = 7 (47%) | n = 15 (41%) | n = 6 (60%) | ||
| 2 | n = 10 (27%) | n = 3 (20%) | n = 6 (16%) | n = 2 (20%) | ||
| > 2 | n = 4 (11%) | n = 1 (7%) | n = 5 (14%) | n = 0 (0%) | ||
| LDH (UI/L) | 288 ± 127 | 371 ± 100 | 0.002 | 363 ± 135 | 400 ± 83 | 0.18 |
| D-dimer (µg/mL FEU) | 1.6 ± 2.6 | 2.2 ± 2.1 | 0.25 | 1.1 ± 1.0 | 2.0 ± 2.2 | 0.10 |
| CRP (mg/dL) | 9 ± 8 | 11 ± 9 | 0.35 | 6 ± 5 | 16 ± 10 | 0.0002 |
| Lymphocytes(103/uL) | 1.1 ± 0.6 | 1.2 ± 1.2 | 0.63 | 1.2 ± 1.9 | 0.8 ± 0.4 | 0.21 |
| P/F (mmHg) | 236 ± 97 | 153 ± 66 | 0.001 | 243 ± 92 | 126 ± 47 | 0.00009 |
| % Consolidation | 5 ± 4 | 13 ± 10 | 0.0007 | 4 ± 4 | 8 ± 6 | 0.017 |
| % Ground glass | 19 ± 16 | 29 ± 16 | 0.008 | 20 ± 15 | 26 ± 10 | 0.06 |
| % Normal lung | 76 ± 18 | 58 ± 20 | 0.0009 | 76 ± 17 | 66 ± 11 | 0.026 |
Continuous values are expressed as mean ± standard deviation.
P/F = ratio between the arterial partial pressure of oxygen [PaO2] measured (in mmHg) by blood gas analysis and fraction of inspired oxygen [FiO2].
CRP serum C-reactive protein, ICU intensive care unit, LDH serum lactate dehydrogenase.