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. 2021 Mar 19;28(8):2450–2464. doi: 10.1038/s41418-021-00762-7

Fig. 6. SNORD50A/B mediates the interaction between TRIM21 and GMPS.

Fig. 6

a HIS-GMPS and TRIM21 were co-expressed in 293 T cells with the indicated treatments, and immunoprecipitation was then performed to determine the effect of SNORD50A/B on the interaction between GMPS and TRIM21. b FAM-labeled SNORD50A or SNORD50B (5 μM) induces a higher polarization of fluorescence when mixed with the combination of TRIM21 and GMPS than each alone. The effect of SNORD50A or SNORD50B on secondary structure of TRIM21 (c) and GMPS (d) proteins. Data were presented as mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001.