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. 2021 Jul 20;15:685715. doi: 10.3389/fnins.2021.685715

FIGURE 5.

FIGURE 5

Activation of PKCε contributes to the transition from acute to chronic pain and TRPV1 expression. Mechanical (A) and thermal (B) responses of animals to the injection of a special PKCε activator. n = 6. The quantification of the Western blot results and a representative Western blot showing PKCε (C) and TRPV1 (D) protein isolated from the DRG 48 h after PGE2 and ψεRACK injection. (E) PKCε and TRPV1 staining in the peripheral nervous system 48 h after PGE2 and ψεRACK injection. Scale bar 100 μm. The quantification of PKCε–IR positive (F) and TRPV1–IR positive (G) neurons.