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. 2021 Jul 20;15:685715. doi: 10.3389/fnins.2021.685715

FIGURE 6.

FIGURE 6

Electroacupuncture (EA) regulates the transition from acute to chronic pain and the PKCε activation and TRPV1 expression in the DRG. The protocol of EA administration (A). Mechanical (B) and thermal (C) responses of hyperalgesic priming model animals to EA and sham EA administration. n = 5–6. (D) PKCε and TRPV1 staining in the peripheral nervous system 48 h after PGE2 injection. Scale bar 100 μm. The quantification of PKCε–IR positive (E) and TRPV1–IR positive (F) neurons. The quantification of the ratio of TRPV1 labeled cells expressing PKCε (G). The quantification of the Western blot results and a representative Western blot showing PKCε (H) and TRPV1 (I) protein isolated from the DRG 48 h after PGE2 injection. △, △△ Compared with the NS+PGE2 group, P < 0.05, P < 0.01; #,## compared with the Car+PGE2 group, P < 0.05, P < 0.01.