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. 2021 Jul 3;297(2):100939. doi: 10.1016/j.jbc.2021.100939

Table 1.

Histone lysine methylation enzymes in budding yeast

Typea Enzyme UniProt ID SGD ID Alias Specificity ECb Chromosome Coordinates Copies/cellc Human orthologd
MTase Set1p P38827 YHR119W KMT2 H3K4me1/2/3 2.1.1.354 VIII 346043–349285 172 SETD1A
Set2p P46995 YJL168C KMT3 H3K36me1/2/3 2.1.1.359 X 102227–104428 217 SETD2
Dot1p Q04089 YDR440W KMT4 H3K79me1/2/3 2.1.1.360 IV 1342493–1344241 2160 DOT1L
Set5p P38890 YHR207C - H4K5/8/12me1 - VIII 514905–516485 5000 SMYD3
DMase Jhd1p P40034 YER051W KDM2 H3K36me1/2 1.14.11.27 V 254656–256134 784 FBXL11
Jhd2p P47156 YJR119C KDM5 H3K4me1/2/3 1.14.11.67 X 644304–646490 290 JARID1C
Rph1p P39956 YER169W KDM4 H3K36me2/3 1.14.11.27 V 523369–525759 2229 JMJD2A
Gis1p Q03833 YDR096W KDM4 H3K36me1/2 1.14.11.27 IV 637139–639823 432 JMJD2A
a

Methyltransferase (MTase) or demethylase (DMase).

b

Enzyme Commission number.

c

Under log-phase growth in synthetic defined medium (346).

d

From Alliance of Genome Resources Release 4.0.0 (347).