Table 1. Baseline characteristics of the enrolled patients.
| Characteristics | Number of patients |
|---|---|
| Overall (%) | 363 (100) |
| Age (years) | |
| <67 | 176 (48.49) |
| ≥67 | 187 (51.51) |
| Mean ± S.D | 66.1 ± 11.4 |
| Range | 27–95 |
| Gender, n (%) | |
| Male | 239 (65.84) |
| Female | 124 (34.16) |
| Smoking history, n (%) | |
| Former/current | 219 (60.33) |
| Never | 144 (39.67) |
| ECOG score | |
| 0 | 224 (61.71) |
| 1 | 139 (38.29) |
| Histological types, n (%) | |
| Adenocarcinoma | 191 (52.62) |
| SCC | 172 (47.38) |
| Clinical stage, n (%) | |
| IIIB | 75 (20.66) |
| IIIC | 9 (2.48) |
| IVA | 146 (40.22) |
| IVB | 133 (36.64) |
| Pathological differentiation, n (%) | |
| Well | 82 (22.59) |
| Moderate | 175 (48.21) |
| Poor | 106 (29.20) |
| NSE level (ng/ml) | |
| Mean ± SD | 20.1 ± 23.7 |
| Range | 0.1–285.2 |
| Brain metastasis | |
| Yes | 53 (14.60) |
| No | 310 (85.40) |
| EGFR status (adenocarcinoma) | |
| Mutation | 87 (45.55) |
| Wildtype | 80 (41.88) |
| Unknown | 24 (12.57) |