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. 2021 Jul 20;12:707784. doi: 10.3389/fimmu.2021.707784

Figure 5.

Figure 5

M1NVs inhibited the development of endometriosis in a murine model. (A) Flow diagram of the experiment in vivo. (B) Typical ectopic endometrial lesion could be found in the peritoneal cavity of the mouse model 14 days after uterus fragment injection. (C) Immunofluorescence staining showed the ectopic lesion had typical endometrial glands (E-cadherin positive, red) and stroma (Vimentin positive, green) (Scale bar =100 μm). (D) Ectopic lesions in different groups. (E, F) Treatment of M1NVs significantly reduced the volume and weight of lesions. (ns: no significance when compared with EM. *P<0.05, **P<0.01 when compared with EM). (G) The count of lesions was not different among groups.