FIGURE 1.

Movement of 10-day old rat pups in open field task. (A) Definition of outer and inner portions of the open field. (B) Movement measures in nicotine and control animals reveals significant effect of MPNE on offspring exploration (see Methods for measures description). On each box, the central mark indicates the median, and the bottom and top edges of the box indicate the 25th and 75th percentiles, respectively. The whiskers extend to ±3SD, and red marks show data points outside of 3SD range.