Table 1. Baseline Characteristics of the Modified Intention-to-Treat Populationa.
| Characteristic | Patients, No. (%) | |
|---|---|---|
| DTAS (n = 74) | DTCT (n = 73) | |
| Age, mean (SD), y | 71.8 (13.1) | 75.6 (12.3) |
| Sex | ||
| Male | 38 (51.4) | 32 (43.8) |
| Female | 36 (48.6) | 41 (56.2) |
| Prestroke mRS score, median (IQR)b | 1 (0-1) | 1 (0-1) |
| Prestroke mRS score | ||
| 0 | 26 (35.1) | 22 (30.1) |
| 1 | 31 (41.9) | 36 (49.3) |
| 2 | 14 (19.4) | 14 (19.2) |
| >2 | 3 (4.1) | 1 (1.4) |
| Risk factors | ||
| Hypertension | 56 (75.7) | 46 (63.0) |
| Diabetes | 10 (13.5) | 19 (26.0) |
| Dyslipidemia | 31 (41.9) | 38 (52.1) |
| Atrial fibrillation | 21 (28.4) | 23 (31.5) |
| Previous stroke | 12 (16.2) | 9 (12.3) |
| Ischemic heart disease | 11 (14.9) | 15 (20.5) |
| Current smoker | 11 (14.9) | 21 (28.8) |
| Previous stroke | 12 (16.2) | 9 (12.3) |
| RACE score, median (IQR)c | 7 (6-8) | 7 (6-8) |
| NIHSS score, median (IQR)d | 17 (14-21) | 18 (14-22) |
| Onset or LTSW to door time, mean (SD), min | 233.6 (106.3) | 240.2 (130.7) |
| Primary/transferred | 19/55 (25.7/74.3) | 21/52 (28.8/71.2) |
| Unknown onset | 15 (20.3) | 7 (9.6) |
| ASPECTS at PSC, median (IQR) | 10 (9-10) | 10 (9-10) |
| Off-hours | 40 (54.0) | 50 (68.5) |
| Intravenous thrombolysis | 37 (50.0) | 39 (53.4) |
| Tandem occlusion | 11 (14.9) | 11 (15.1) |
| Endovascular treatment | 74 (100) | 64 (87.7) |
Abbreviations: ASPECTS, Alberta Stroke Program Early Computed Tomography Score; DTAS, direct transfer to angiography suite; DTCT, direct transfer to computed tomography; IQR, interquartile range; LTSW, last time seen well; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PSC, primary stroke center; RACE, Rapid Arterial Occlusion Evaluation.
Modified intention-to-treat population was defined as patients with large vessel occlusion. There were no significant differences between groups.
The mRS scores of functional disability range from 0 (no symptoms) to 6 (death). A score of 2 or lower indicates functional independence.
The RACE scale ranges from 0 to 9, with higher values indicating more severe stroke symptoms.
The NIHSS ranges from 0 to 42, with higher values indicating more severe stroke symptoms.