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. 2021 Aug 2;78(9):1–9. doi: 10.1001/jamaneurol.2021.2385

Table 2. Primary and Secondary Clinical Outcomesa.

Outcome Patients, % Effect variable Odds ratio (95% CI)
DTAS (n = 74) DTCT (n = 73) Unadjusted Adjusted
Shift analysis
90-d mRS scoreb NA NA Common odds ratio 2.0 (1.1-3.7) 2.2 (1.2-4.1)
90-d mRS score (unified 5-6) NA NA Common odds ratio 2.1 (1.2-3.7) 2.2 (1.2-4.0)
90-d mRS score
0-2 43.2 27.4 Odds ratio 2.0 (1.0-4.0) 2.0 (0.8-4.8)
0-3 58.1 45.2 Odds ratio 1.7 (0.9-3.2) 1.9 (0.8-4.3)
90-d mortalitya 21.3 32.9 Odds ratio 0.6 (0.3-1.1) 0.5 (0.2-1.2)

Abbreviations: DTAS, direct transfer to angiography suite; DTCT, direct transfer to computed tomography; mRS, modified Rankin Scale; NA, not applicable.

a

Primary and secondary efficacy outcomes were evaluated in the modified intention-to-treat population, defined as patients with large vessel occlusion, whereas 90-day mortality was evaluated in all patients. The DTAS protocol improved clinical outcome, showing an adjusted common odds ratio of improvement of 1 point on the mRS score of 2.2.

b

The mRS scores of functional disability range from 0 (no symptoms) to 6 (death), with a score of 2 or lower indicating functional independence.