Table 3. Workflow and Procedural Characteristics of the Modified Intention-to-Treat Populationa.
Characteristic | Patients, No. (%) | P value | |
---|---|---|---|
DTAS (n = 74) | DTCT (n = 73) | ||
Patients receiving EVT | |||
Door-to-puncture time, median (IQR), min | 18 (15-24) | 42 (35-51) | <.001 |
No. of passes, median (IQR) | 2 (1-3) | 2 (1-3) | .22 |
Onset-to-reperfusion time, mean (SD), min | 290.5 (141.7) | 326.9 (122.2) | .32 |
Door-to-reperfusion time, median (IQR), min | 57 (43-77) | 84 (63-117) | <.001 |
Occlusion level | |||
TICA | 18 (24.3) | 17 (23.3) | .28 |
M1-MCA | 40 (54.1) | 32 (43.8) | |
M2-MCA | 11 (14.9) | 22 (30.1) | |
PCA | 1 (1.35) | 0 | |
BA | 2 (2.7) | 1 (1.3) | |
Multiple vessel | 2 (2.7) | ||
mTICI grade (patients receiving EVT)b | |||
0 | 3 | 4 | .82 |
1 | 1 (1.35) | 0 | |
2a | 6 | 4 | |
2b | 20 | 14 | |
2c | 16 | 13 | |
3 | 28 | 29 | |
mTICI grades 2b-3 (patients receiving EVT) | 64 (86.4) | 56 (87.5) | .86 |
Severe procedure complication | 6 (8.1) | 2 (2.7) | .6 |
24-h NIHSS score, median (IQR)c | 11 (3-18.5) | 15 (6.5-20) | .24 |
Dramatic recovery | 25 (33.8) | 21 (28.8) | .51 |
Symptomatic hemorrhage | 1 (1.4) | 3 (4.1) | .28 |
Hemicraniectomy | 2 (2.7) | 4 (5.5) | .39 |
Discharge/5-d NIHSS score, median (IQR) | 6.5 (1-14) | 11 (4-19) | .11 |
In-hospital mortality | 5 (6.8) | 8 (11.0) | .39 |
Vascular access complication | 2 (2.7) | 0 | .16 |
Abbreviations: BA, basilar artery; DTAS, direct transfer to angiography suite; DTCT, direct transfer to computed tomography; EVT, endovascular treatment; IQR, interquartile range; MCA, middle cerebral artery; mTICI, modified treatment in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; PCA, posterior cerebral artery; TICA, terminal internal carotid artery.
Modified intention-to-treat population defined as patients with large vessel occlusion; DTAS showed shorter door-to-puncture and door-to-reperfusion times than DTCT.
The mTICI scale assesses reperfusion status, which ranges from 0 (no reperfusion) to 3 (complete reperfusion).
Scale ranges from 0 to 42, with higher values indicating more severe stroke symptoms.