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. 2021 Aug 2;78(9):1–9. doi: 10.1001/jamaneurol.2021.2385

Table 3. Workflow and Procedural Characteristics of the Modified Intention-to-Treat Populationa.

Characteristic Patients, No. (%) P value
DTAS (n = 74) DTCT (n = 73)
Patients receiving EVT
Door-to-puncture time, median (IQR), min 18 (15-24) 42 (35-51) <.001
No. of passes, median (IQR) 2 (1-3) 2 (1-3) .22
Onset-to-reperfusion time, mean (SD), min 290.5 (141.7) 326.9 (122.2) .32
Door-to-reperfusion time, median (IQR), min 57 (43-77) 84 (63-117) <.001
Occlusion level
TICA 18 (24.3) 17 (23.3) .28
M1-MCA 40 (54.1) 32 (43.8)
M2-MCA 11 (14.9) 22 (30.1)
PCA 1 (1.35) 0
BA 2 (2.7) 1 (1.3)
Multiple vessel 2 (2.7)
mTICI grade (patients receiving EVT)b
0 3 4 .82
1 1 (1.35) 0
2a 6 4
2b 20 14
2c 16 13
3 28 29
mTICI grades 2b-3 (patients receiving EVT) 64 (86.4) 56 (87.5) .86
Severe procedure complication 6 (8.1) 2 (2.7) .6
24-h NIHSS score, median (IQR)c 11 (3-18.5) 15 (6.5-20) .24
Dramatic recovery 25 (33.8) 21 (28.8) .51
Symptomatic hemorrhage 1 (1.4) 3 (4.1) .28
Hemicraniectomy 2 (2.7) 4 (5.5) .39
Discharge/5-d NIHSS score, median (IQR) 6.5 (1-14) 11 (4-19) .11
In-hospital mortality 5 (6.8) 8 (11.0) .39
Vascular access complication 2 (2.7) 0 .16

Abbreviations: BA, basilar artery; DTAS, direct transfer to angiography suite; DTCT, direct transfer to computed tomography; EVT, endovascular treatment; IQR, interquartile range; MCA, middle cerebral artery; mTICI, modified treatment in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; PCA, posterior cerebral artery; TICA, terminal internal carotid artery.

a

Modified intention-to-treat population defined as patients with large vessel occlusion; DTAS showed shorter door-to-puncture and door-to-reperfusion times than DTCT.

b

The mTICI scale assesses reperfusion status, which ranges from 0 (no reperfusion) to 3 (complete reperfusion).

c

Scale ranges from 0 to 42, with higher values indicating more severe stroke symptoms.