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. 2021 Jul 7;22(14):7292. doi: 10.3390/ijms22147292

Figure 2.

Figure 2

Brain neuropathology, microscopic anatomy: (A) immunohistochemistry staining showing tau accumulation in the putamen, predominantly in the form of tufted astrocytes and tau-positive neurons (100× magnification); (B) immunohistochemistry staining showing tufted astrocytes in the caudate nucleus (200× magnification); (C,D) substantia nigra showing neuronal cell loss, tau-positive neurons, and numerous neuropil threads ((C) hematoxylin and eosin staining; (D) immunohistochemistry staining; 100× magnification).