Table 1.
Clinical and other relevant characteristics (demographic, lung function, asthma features, comorbidity etc.) of the cohort (at baseline). SD- standard deviation, M- male, F- female, BMI- body mass index, AR- allergic rhinitis, AD- atopic dermatitis, GERD- gastroesophageal reflux disease, RI- reflux index, OSA- obstructive sleep apnoea, AHI- apnoea/hypopnea index, IgE- immunoglobulin E, WBC- white blood cells, hsCRP- high-sensitivity C-reactive protein. Percentile of BMI- underweight (≤ 5), normal (5–85), overweight (86–94), obese (≥ 95)
| Age (years)- (mean, SD) | 9.97 (3.97) | |
| M- 9.68 (3.93) | F- 10.44 (4.01) | |
| Gender (M/F)- N (%) | M 223 (61.10) | F 142 (38.90) |
| Percentile of BMI- N (%) | Underweight | 11 (3.01) |
| Normal | 253 (69.32) | |
| Overweight | 50 (13.70) | |
| Obese | 51 (13.97) | |
| Duration of disease (years)- mean (SD) | 3.27 (2.83) N = 302 | |
| Comorbidities- N (%), mean (SD) | AR | 312 (85.48) |
| AD ever | 101 (27.67) | |
| AD currently | 23 (6.33) | |
| GERD, RI score | 101 (27.82), 9.10 (SD- 11.19) | |
| OSA, AHI | 14 (3.84), 0.57 (SD- 2.84) | |
| Atopy (yes/no)- N (%) | Yes | 319 (87.40) |
| No | 46 (12.60) | |
| Total IgE (kIU/l)- mean (SD) | 614.54 (1145.62), N = 351 | |
| Eosinophil count (absolute)- median (SD) | 416.35 (341.27), N = 355 | |
| Neutrophil count (% of total WBC)- mean (SD) | 49.76 (12.86), N = 364 | |
| hsCRP (mg/l)- mean (SD) | 2.23 (9.30), N = 311 | |
| Lung FENO (ppb)- mean (SD) | 20.49 (20.07), N = 350 | |
| % of FEV1 predicted- mean (SD) | 87 (17.14) | |
| % of MEF50 predicted- mean (SD) | 88 (23.11) | |