Table 1.
HScore
| Parameter | Score |
|---|---|
| Known underlying immunosuppression¸ HIV positive, Immunosuppressive drugs | |
| No | 0 |
| Yes | 18 |
| Maximal temperature (C) | |
| < 38.4 | 0 |
| 38.4–39.4 | 33 |
| > 39.4 | 49 |
| Organomegaly | |
| No | 0 |
| Hepatomegaly or splenomegaly | 23 |
| Hepatomegaly & splenomegaly | 38 |
| Number of cytopenias (Hb ≤ 9.2 g/dL, WBC ≤ 5000/μl, PLT ≤ 110,000/μl) | |
| 1 lineage | 0 |
| 2 lineages | 24 |
| 3 lineages | 34 |
| Higher ferritin level (ng/ml) | |
| < 2000 | 0 |
| 2000–6000 | 35 |
| > 6000 | 50 |
| Higher triglyceride level (mg/dL) | |
| < 133.5 | 0 |
| 133.5–356 | 44 |
| > 356 | 64 |
| Lower fibrinogen level (g/L) | |
| > 250 | 0 |
| ≤ 250 | 30 |
| Higher SGOT/AST level (IU/L) | |
| < 30 | 0 |
| ≥ 30 | 19 |
| Hemophagocytosis features on bone marrow aspirate | |
| No | 0 |
| Yes | 35 |
| Total score | |
HIV human immunodeficiency virus, Hb hemoglobin, WBC white blood cell, PLT platelet, SGOT serum glutamic-oxaloacetic transaminase, AST aspartate aminotransferase