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. 2021 Aug 3;138:182–188. doi: 10.1016/j.jclinepi.2021.07.021

Table 1.

Risk of bias assessment for the reference standard in Cochrane reviews of diagnostic tests for COVID-19

Author [Reference] Test(s) No. of studies No. of participants* No. (%) of studies at high risk of bias No. (%) of studies at unclear risk of bias No. (%) of studies at low risk of bias
Struyf et al. [11] Signs and symptoms 44 26,884 3 (7) 8 (18) 33 (75)
Stegeman et al. [12] Routine laboratory tests 21 70,711 14 (67) 5 (24) 2 (10)
Dinnes et al. [13] Rapid, point-of-care antigen and molecular-based tests 78 24,087 66 (85) 6 (8) 6 (8)
Deeks et al. [14] Antibody tests 54 15,976 17 (31) 24 (24) 13 (24)
Islam et al. [15] Thoracic imaging tests 51 19,775 20 (39) 20 (39) 11 (22)
TOTAL - 248 157,433 120 (48) 63 (25) 65 (26)

* or samples

Table updated on May 20th, 2021